Bubble Up Pizza Casserole with Biscuits
Bubble Up Pizza Casserole with Biscuits is a delicious, easy casserole with a soft garlic parmesan biscuit base topped with rich tomato sauce, gooey cheese, and pepperoni. Fast, easy dinner recipe that takes just a few minutes of prep time and bakes in about 30 minutes.
For a complete meal, serve with a fresh Caprese Salad, Roasted Green Beans, or a bowl of Tuscan Kale Soup.
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The first time I made this bubble up pizza casserole recipe, I ended up making it 3 times in one week. It's so good!
The fluffy biscuits seasoned with Parmesan garlic butter bake into the most delicious thick, puffy pizza crust. Topped with gooey mozzarella and pepperoni, it kind of reminds us of a lazy version of a deep-dish pizza.
And it's so fast and easy to make with just a handful of ingredients.
You're Going to Love This
- Delicious dinner for busy weeknights or pizza night the whole family will request again and again
- Perfect weeknight meal you can make ahead the night before or in the morning and bake when you get home
- Fast, fun way to satisfy your pizza cravings without pizza delivery!
Ingredients
See recipe card at the bottom of the post for the full list of ingredients and exact amounts.
Refrigerated biscuit dough. You'll need one 16.3 oz. (8 count) can of biscuits, such as Pillsbury Grands! Southern Homestyle biscuits.
Parmesan cheese. For best flavor, use freshly grated Parmesan. If that's not doable, try to find freshly grated Parmesan that comes in a bag or tub -- not the green shaker.
Italian seasoning. If you don't have Italian seasoning, use equal parts dried basil, oregano, and thyme. You can also add dried rosemary and parsley if you have it.
Pizza sauce. 16 ounces might seem like A LOT of sauce, but the biscuits absorb some of it, so it's really the perfect amount. Our favorite brand is Pastorelli.
Shredded mozzarella cheese. If possible, shred your own cheese -- it melts much creamier than pre-bagged cheese because it doesn't have all that anti-caking stuff on it. You can also use your favorite pizza cheeses like fontina, provolone, cheddar cheese, or a blend.
Toppings. Instead of or in addition to pepperoni slices, go ahead and add cooked sausage, green peppers, black olives, onions, or whatever your favorite pizza toppings are.
How to Make Bubble Up Pizza Casserole with Biscuits
Step 1: Cut each biscuit into 8 pieces by cutting the biscuit in half across the equator, then cutting each half in half, then cutting each of those halves in half. Place the biscuit pieces in a 9 x 13 casserole dish coated with nonstick cooking spray.
Step 2: In the baking dish, toss the biscuits with melted butter, garlic powder, Italian seasoning, and Parmesan cheese.
Step 3: Spread the pizza sauce over the biscuits, then
Step 4: Layer on the cheese and pepperoni or your favorite toppings. If desired, sprinkle with more Italian seasoning and red pepper flakes.
Step 5: Cover with aluminum foil and bake in preheated oven at 400 for 20 minutes.
Remove the foil and bake 5-10 more minutes or until the biscuits are baked through.
Step 6: Let it rest for 5 minutes before serving.
Serve with Italian Zucchini Salad or roasted vegetables for a complete meal.
Expert Tips
- For best flavor and gooeyness, use freshly grated Parmesan and shredded mozzarella cheese.
- Check the center biscuits for doneness by removing one with a fork and testing it or checking with a digital thermometer -- the internal temperature should be from 205 to 210 degrees.
- Make this bubble up pizza casserole recipe ahead of time. Assemble, cover with foil or plastic wrap, and refrigerate for up to a day. Let it sit at room temp for 30 minutes, then bake as directed. You may need to add a few minutes of baking time.
FAQs
Store leftover bubble-up pizza casserole in an airtight container in the refrigerator for 3-4 days.
Bubble up pizza bake is best enjoyed freshly from the oven. The best way to warm it up is to place it in a 350-degree preheated oven, covered with foil for 25-30 minutes or until warmed through to 165 degrees. You can also reheat single servings in the microwave in 30-second increments until warm -- be careful not to over-nuke, or it gets tough.
Yes! Pizza casserole with biscuits is the perfect dinner to make in advance. Just assemble the casserole, cover it with foil or plastic wrap, and refrigerate up to overnight.
When ready to bake, let it sit at room temperature for 30-60 minutes, then bake as directed. If the pizza casserole is still cold going into the oven, you may need to add a few minutes of cooking time.
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📖 Recipe
Bubble Up Pizza Casserole
Ingredients
- 1 tube Pillsbury Grands! Southern Homestyle Biscuits (8 count, 16.3 ounces)
- 4 tablespoons melted butter
- 1 teaspoon garlic powder
- ½ teaspoon Italian seasoning
- ¼ cup grated Parmesan cheese
- 16 ounces pizza sauce
- 2 cups shredded Mozzarella cheese
- 20-24 slices pepperoni
- red pepper flakes, optional
Instructions
- Preheat oven to 400 degrees. Coat 9x13 pan with nonstick spray.
- Cut each biscuit into 8 pieces and place in pan. Toss biscuit pieces with the butter, garlic powder, Italian seasoning, and Parmesan. Arrange into an even layer in the pan.
- Evenly spread pizza sauce over the biscuit dough. Top with mozzarella and pepperoni. If desired, sprinkle with more Italian seasoning and red pepper flakes.
- Cover pan with foil and bake 20 minutes. Remove foil and bake 5-10 more minutes or until the biscuits are done. Let it rest for 5 minutes before serving.
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Notes
- For best flavor and gooeyness, use freshly grated Parmesan and shredded mozzarella cheese.
- Check the center biscuits for doneness by removing one with a fork and testing it or checking with a digital thermometer -- the internal temperature should be from 205 to 210 degrees.
- Make this bubble up pizza casserole recipe ahead of time. Assemble, cover with foil or plastic wrap, and refrigerate for up to a day. Let it sit at room temp for 30 minutes, then bake as directed. You may need to add a few minutes of baking time.
This was really good! I cut the garlic in half and used shredded Italian cheese blend in place of the Parmesan since I didn’t have any on hand. Added red onion and red pepper. No pepperoni (this time). This easily satisfied my pizza craving for a fraction of the take-out price.
That's fantastic, I'm so glad you enjoyed it! Thanks for the nice note :). Cara